Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLK4 All Species: 1.21
Human Site: S115 Identified Species: 3.33
UniProt: Q5TCX8 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5TCX8 NP_115811.2 1036 113957 S115 P P P S R P S S P V H V A F E
Chimpanzee Pan troglodytes XP_001146659 1107 121909 S130 R C L P G K E S P T Y S A A A
Rhesus Macaque Macaca mulatta XP_001103092 1040 114439 P115 P P P A P P P P R P S S P V H
Dog Lupus familis XP_547887 1216 135201 G195 Q K L T S G S G A Q V L S K R
Cat Felis silvestris
Mouse Mus musculus Q8VDG6 1002 110093 L110 V H V D F E R L E L K E L I G
Rat Rattus norvegicus Q66HA1 850 93091 G94 G Q V G G Q V G I F P S N Y V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q7T2V3 1005 111856 L109 G A P K Q C P L P L E I E F D
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95UN8 1161 128942 Q133 S S A I G D I Q P H E I E Y N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O01700 928 103465 F112 F Q P V F G Y F G T K T T V E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.1 95 44.7 N.A. 69.5 45.7 N.A. N.A. N.A. 47.2 N.A. N.A. 31.2 N.A. 20.4 N.A.
Protein Similarity: 100 63.9 96.1 57.8 N.A. 76.9 58.2 N.A. N.A. N.A. 62.5 N.A. N.A. 45.2 N.A. 35.8 N.A.
P-Site Identity: 100 20 26.6 6.6 N.A. 0 0 N.A. N.A. N.A. 20 N.A. N.A. 6.6 N.A. 13.3 N.A.
P-Site Similarity: 100 26.6 33.3 26.6 N.A. 6.6 6.6 N.A. N.A. N.A. 46.6 N.A. N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 12 0 0 0 0 12 0 0 0 23 12 12 % A
% Cys: 0 12 0 0 0 12 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 12 0 12 0 0 0 0 0 0 0 0 12 % D
% Glu: 0 0 0 0 0 12 12 0 12 0 23 12 23 0 23 % E
% Phe: 12 0 0 0 23 0 0 12 0 12 0 0 0 23 0 % F
% Gly: 23 0 0 12 34 23 0 23 12 0 0 0 0 0 12 % G
% His: 0 12 0 0 0 0 0 0 0 12 12 0 0 0 12 % H
% Ile: 0 0 0 12 0 0 12 0 12 0 0 23 0 12 0 % I
% Lys: 0 12 0 12 0 12 0 0 0 0 23 0 0 12 0 % K
% Leu: 0 0 23 0 0 0 0 23 0 23 0 12 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 12 % N
% Pro: 23 23 45 12 12 23 23 12 45 12 12 0 12 0 0 % P
% Gln: 12 23 0 0 12 12 0 12 0 12 0 0 0 0 0 % Q
% Arg: 12 0 0 0 12 0 12 0 12 0 0 0 0 0 12 % R
% Ser: 12 12 0 12 12 0 23 23 0 0 12 34 12 0 0 % S
% Thr: 0 0 0 12 0 0 0 0 0 23 0 12 12 0 0 % T
% Val: 12 0 23 12 0 0 12 0 0 12 12 12 0 23 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 12 0 0 0 12 0 0 23 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _